Publications

2024

Storz JF, Scott GR. 2024. To what extent do physiological tolerances determine elevational range limits of mammals? J Physiol. Accepted.

Garrett EJ, Prasad SK, Schweizer RM, McClelland GB, Scott GR. 2024. Evolved changes in phenotype across skeletal muscles in deer mice native to high altitude. Am J Physiol Reg Integr Comp Physiol. 326, R297-R310.

Taylor PJ, Nengovhela A, Denys C, Scott GR, Ivy CM. 2024. Adaptation in brain structure and respiratory and olfactory structures across environmental gradients in African and North American muroid rodents. Int Zool. 19, 165-181.

2023

Schell ER, McCracken KG, Scott GR, White J, Lavretsky P, Dawson NJ. 2023. Consistent changes in muscle metabolism underlie dive performance across multiple lineages of diving ducks. Proc R Soc B. 290, 20231466.

Schweizer RM, Ivy CM, Natarajan C, Scott GR, Storz JF, Cheviron ZA. 2023. Gene regulatory changes underlie developmental plasticity in respiration and aerobic performance in highland deer mice. Mol Ecol. 32, 3483-3496.

Ridgway MR, Scott GR. 2023. Constant temperature and fluctuating temperature have distinct effects on hypoxia tolerance in killifish (Fundulus heteroclitus). J Exp Biol. 226, jeb245425.

Nengovhela A, Ivy CM, Scott GR, Denys C, Taylor PJ. 2023. Counter-gradient variation and the expensive tissue hypothesis explain parallel brain size reductions at high elevation in Cricetid and Murid rodents. Sci Rep. 13, 5617.

Flewwelling LD, Wearing OH, Garrett EJ, Scott GR. 2023. Thermoregulatory trade-offs underlie the effects of warming summer temperatures on deer mice. J Exp Biol. 226, jeb244852.
[ECR Spotlight]

Eizenga MR, Flewwelling LD, Warrier T, Scott GR. 2023. Thermal performance curve of endurance running at high temperatures in deer mice. J Exp Biol. 226, jeb244847.
[Inside JEB Feature]

Mahalingam S, Coulson SZ, Scott GR, McClelland GB. 2023. Function of left ventricle mitochondria in highland deer mice and lowland mice. J Comp Physiol B. 193, 207-217.

2022

Wearing OH, Scott GR. 2022. Sex-specific effects of chronic hypoxia on routine cardiovascular function and metabolism in CD-1 mice. Am J Physiol Reg Integr Comp Physiol. 323, R547-R560.

Wearing OH, Scott GR. 2022. Evolved reductions in body temperature and the metabolic costs of thermoregulation in deer mice native to high altitude. Proc R Soc B. 289, 20221553.

Ivy CM, Velotta JP, Cheviron ZA, Scott GR. 2022. Genetic variation in HIF-2α attenuates ventilatory sensitivity and carotid body growth in chronic hypoxia in high-altitude deer mice. J Physiol. 600, 4207-4225.
[Perspective Article]

Yu JJ, Non AL, Heinrich EC, Gu W, Alcock J, Moya EA, Lawrence ES, Tift MS, O’Brien KA, Storz JF, Signore AV, Khudyakov JI, Milsom WK, Wilson SM, Beall CM, Villafuerte FC, Stobdan T, Julian CG, Moore LG, Fuster MM, Stokes JA, Milner R, West JB, Zhang J, Shyy JY, Childebayeva A, Vázquez-Medina JP, Pham LV, Mesarwi OA, Hall JE, Cheviron ZA, Sieker J, Blood AB, Yuan JX, Scott GR, Rana BK, Ponganis PJ, Malhotra A, Powell FL, Simonson TS. 2022. Time domains of hypoxia responses and -omics insights. Front Physiol. 13, 885295.

Dawson NJ, Scott GR. 2022. Adaptive increases in respiratory capacity and O2 affinity of subsarcolemmal mitochondria from skeletal muscle of high-altitude deer mice. FASEB J. 36, e22391.

Wearing OH, Nelson D, Ivy CM, Crossley DA, Scott GR. 2022. Adrenergic control of the cardiovascular system in deer mice native to high altitude. Curr Res Physiol. 5, 83-92.

Mehdi H, Morphet ME, Lau SC, Bragg LM, Servos MR, Parrott JL, Scott GR, Balshine S. 2022. Temperature modulates the impacts of wastewater exposure on the physiology and behaviour of fathead minnows. Chemosphere. 294, 133738.

Ivy CM, Wearing OH, Natarajan C, Schweizer RM, Gutiérrez-Pinto N, Velotta JP, Campbell-Staton SC, Petersen EE, Fago A, Cheviron ZA, Storz JF, Scott GR. 2022. Genetic variation in haemoglobin is associated with evolved changes in breathing in high-altitude deer mice. J Exp Biol. 225, jeb243595.
[Inside JEB Feature]

2021

Turko AJ, Leclair ATA, Mandrak NE, Drake DAR, Scott GR, Pitcher TE. 2021. Choosing source populations for conservation reintroductions: lessons from variation in thermal tolerance among populations of the imperilled redside dace. Can J Fish Aquat Sci. 78, 1347-1355.

Scott GR, Dalziel AC. 2021. Physiological insight into the evolution of complex phenotypes: aerobic performance and the O2 transport pathway of vertebrates. J Exp Biol. 224, jeb210849.
[Big Biology Podcast]

Borowiec BG, Scott GR. 2021. Rapid and reversible modulation of blood haemoglobin content during diel cycles of hypoxia in killifish (Fundulus heteroclitus). Comp Biochem Physiol A. 261, 111054.

Ivy CM, Prest H, West CM, Scott GR. 2021. Distinct mechanisms underlie developmental plasticity and adult acclimation of thermogenic capacity in high-altitude deer mice. Front Physiol. 12, 718163.

Wearing OH, Ivy CM, Gutiérrez-Pinto N, Velotta JP, Campbell-Staton SC, Natarajan C, Cheviron ZA, Storz JF, Scott GR. 2021. The adaptive benefit of increases in hemoglobin-O2 affinity is contingent upon tissue O2 diffusing capacity in high-altitude deer mice. BMC Biol. 19, 128.

Wearing OH, Scott GR. 2021. Commentary: Hierarchical reductionism approach to understanding adaptive variation in animal performance. Comp Biochem Physiol B. 256, 110636.

Lau SC, Mehdi H, Bragg LM, Servos MR, Balshine S, Scott GR. 2021. Exposure to wastewater effluent disrupts hypoxia responses in killifish (Fundulus heteroclitus). Environ Pollut. 284, 117373.

West CM, Wearing OH, Rhem RG, Scott GR. 2021. Pulmonary hypertension is attenuated and ventilation-perfusion matching is maintained during chronic hypoxia in deer mice native to high altitude. Am J Physiol Reg Integr Comp Physiol. 320, R800-R811.
[APSselect article]

Vandenberg GG, Dawson NJ, Head A, Scott GR, Scott AL. 2021. Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model. Neurochem Int. 146, 105036.

Parr N, Dawson NJ, Ivy CM, Morten JM, Scott GR, Hawkes LA. 2021. Flight muscle and heart phenotypes in the high-flying ruddy shelduck. J Comp Physiol B. 191, 563-‌573.

Nikel KE, McCallum ES, Mehdi H, Du SNN, Bowman JE, Midwood JD, Scott GR, Balshine S. 2021. Fish living near two wastewater treatment plants have unaltered thermal tolerance but show changes in organ and tissue traits. J Great Lakes Res. 47, 522-533.

West CM, Ivy CM, Husnudinov R, Scott GR. 2021. Evolution and developmental plasticity of lung structure in high-altitude deer mice. J Comp Physiol B. 191, 385-396.

Ivy CM, Scott GR. 2021. Life-long exposure to hypoxia affects metabolism and respiratory physiology across life stages in high-altitude deer mice (Peromyscus maniculatus). J Exp Biol. 224, jeb237024.

Mehdi H, Lau SC, Synyshyn C, Salenaa MG, McCallum ES, Muzzatti MN, Bowman JE, Mataya KJ, Bragg LM, Servos MR, Kidd KA, Scott GR, Balshine S. 2021. Municipal wastewater as an ecological trap: effects on fish communities across seasons. Sci Total Environ. 759, 143430.

Milsom WK, Scott GR, McCracken KG, Frappell PB. 2021. Different strategies for convective O2 transport in high altitude birds: a graphical analysis. Comp Biochem Physiol A. 253, 110871.

Storz JF, Scott GR. 2021. Phenotypic plasticity, genetic assimilation, and genetic compensation in hypoxia adaptation of high-altitude vertebrates. Comp Biochem Physiol A. 253, 110865.

2020

Mahalingam S, Cheviron ZA, Storz JF, McClelland GB, Scott GR. 2020. Chronic cold exposure induces mitochondrial plasticity in deer mice native to high altitudes. J Physiol. 598, 5411-5426.
[Editor’s Choice article]

Dawson NJ, Alza L, Nandal G, Scott GR, McCracken KG. 2020. Convergent changes in muscle metabolism depend on duration of high-altitude ancestry across Andean waterfowl. eLife. 9, e56259.

Turko AJ, Nolan CB, Balshine S, Scott GR, Pitcher TE. 2020. Thermal tolerance depends on season, age, and body condition in imperiled redside dace Clinostomus elongatus. Conserv Physiol. 8, coaa062.

Borowiec BG, Scott GR. 2020. Hypoxia acclimation alters reactive oxygen species homeostasis and oxidative status in estuarine killifish (Fundulus heteroclitus). J Exp Biol. 223, jeb222877.

Tate KB, Wearing OH, Ivy CM, Cheviron ZA, Storz JF, McClelland GB, Scott GR. 2020. Coordinated changes across the O2 transport pathway underlie adaptive increases in thermogenic capacity in high-altitude deer mice. Proc R Soc B. 287, 20192750.
[Outside JEB Feature]

Gnaiger E et al. – MitoEagle Task Group. 2020. Mitochondrial physiology. Bioenerg Commun. 2020.1.

Dubay SG, Wu Y, Scott GR, Qu Y, Liu Q, Smith J, Xin C, Reeve AH, Juncheng C, Meyers D, Wang J, Johnson J, Cheviron ZA, Lei F, Bates J. 2020. Life history predicts flight muscle phenotype and function in birds. J Anim Ecol. 89, 1262-1276.

Ivy CM, Greaves MA, Sangster ED, Robertson CE, Natarajan C, Storz JF, McClelland GB, Scott GR. 2020. Ontogenesis of evolved changes in respiratory physiology in deer mice native to high altitude. J Exp Biol. 223, jeb219360.

Lague SL, Ivy CM, York JM, Chua BA, Alza L, Cheek R, Dawson NJ, Frappell PB, Farrell AP, McCracken KG, Scott GR, Milsom WK. 2020. Cardiovascular responses to progressive hypoxia in ducks native to high altitude in the Andes. J Exp Biol. 223, jeb211250.

Borowiec BG, Hoffman RD, Hess CD, Galvez F, Scott GR. 2020. Interspecific variation in hypoxia tolerance and hypoxia acclimation responses in killifish from the family Fundulidae. J Exp Biol. 223, jeb209692.

Houpt NSB, Borowiec BG, Bose APH, Brown NAW, Scott GR, Balshine S. 2020. Parental males of the plainfin midshipman are physiologically resilient to the challenges of the intertidal zone. Physiol Biochem Zool. 93, 111-128.

2019

Schweizer RM, Velotta JP, Ivy CM, Jones MR, Muir SM, Bradburd GS, Storz JF, Scott GR, Cheviron ZA. 2019. Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice. PLoS Genet. 15, e1008420.

McLean AR, Du SNN, Choi JA, Culbert BM, McCallum ES, Scott GR, Balshine S. 2019. Proximity to wastewater effluent alters behaviour in bluegill sunfish (Lepomis machrochirus). Behaviour. 156, 1495-1517.

Storz JF, Scott GR. 2019. Life ascending: mechanism and process in physiological adaptation to high-altitude hypoxia. Annu Rev Ecol Evol Syst. 50, 503-526.

Parr N, Bishop CM, Batbayar N, Butler PJ, Chua B, Milsom WK, Scott GR, Hawkes LA. 2019. Tackling the Tibetan Plateau in a down suit: insights into thermoregulation by bar-headed geese during migration. J Exp Biol. 222, jeb203695.

Scott AL, Pranckevicius NA, Nurse CA, Scott GR. 2019. Regulation of catecholamine release from the adrenal medulla is altered in deer mice (Peromyscus maniculatus) native to high altitudes. Am J Physiol Reg Integr Comp Physiol. 317, R407-R417.

Du SNN, Choi JA, McCallum ES, McLean AR, Borowiec BG, Balshine S, Scott GR. 2019. Metabolic implications of exposure to wastewater effluent in bluegill sunfish. Comp Biochem Physiol C. 224, 108562.

Ding Y, Lyons SA, Scott GR, Gillis TE. 2019. Characterizing the influence of chronic hypobaric hypoxia on diaphragmatic myofilament function and phosphorylation in high-altitude deer mice and low-altitude white-footed mice. J Comp Physiol B. 189, 489-499.

McCallum ES, Nikel KE, Mehdi H, Du SNN, Bowman JE, Midwood JD, Kidd KA, Scott GR, Balshine S. 2019. Municipal wastewater effluent affects fish communities: a multi-year study involving two wastewater treatment plants. Environ Pollut. 252, 1730-1741.

Storz JF, Cheviron ZA, McClelland GB, Scott GR. 2019. Evolution of physiological performance capacities and environmental adaptation: insights from high-elevation deer mice (Peromyscus maniculatus). J Mammal. 100, 910-922.

Ivy CM, Lague SL, York JM, Chua BA, Alza L, Cheek R, Dawson NJ, Frappell PB, McCracken KG, Milsom WK, Scott GR. 2019. Control of breathing and respiratory gas exchange in ducks native to high altitude in the Andes. J Exp Biol. 222, jeb198622.

McClelland GB, Scott GR. 2019. Evolved mechanisms of aerobic performance and hypoxia resistance in high-altitude natives. Annu Rev Physiol. 81, 561-583.

Bose APH, Borowiec BG, Scott GR, Balshine S. 2019. Nesting on high: reproductive and physiological consequences of breeding across an intertidal gradient. Evol Ecol. 33, 21-36.

2018

Velotta JP, Ivy CM, Wolf CJ, Scott GR, Cheviron ZA. 2018. Maladaptive phenotypic plasticity in cardiac muscle growth is suppressed in high-altitude deer mice. Evolution. 72, 2712-2727.

Borowiec BG, McClelland GB, B.B. Rees, Scott GR. 2018. Distinct metabolic adjustments arise from acclimation to constant hypoxia and intermittent hypoxia in killifish (Fundulus heteroclitus). J Exp Biol. 221, jeb190900.

Ivy CM, Scott GR. 2018. Evolved changes in breathing and CO2 sensitivity in deer mice native to high altitudes. Am J Physiol Reg Integr Comp Physiol. 315, R1027-R1037.

Scott GR, Guo KH, Dawson NJ. 2018. The mitochondrial basis for adaptive variation in aerobic performance in high-altitude deer mice. Integr Comp Biol. 58, 506-518.

Hood WR, Austad SN, Bize P, Jimenez AG, Montooth KL, Schulte PM, Scott GR, Sokolova I, Treberg JR, Salin K. 2018. The mitochondrial contribution to animal performance, adaptation, and life-history variation. Integr Comp Biol. 58, 480-485.

Nikel KE, Shanishchara NK, Ivy CM, Dawson NJ, Scott GR. 2018. Effects of hypoxia at different life stages on locomotory muscle phenotype in deer mice native to high altitude. Comp Biochem Physiol B. 224, 98-104.

Dawson NJ, Lyons SA, Henry DA, Scott GR. 2018. Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude. Acta Physiol. 223, e13030.

Ivy CM, York JM, Lague SL, Chua BA, Alza L, McCracken KG, Milsom WK, Scott GR. 2018. Validation of a pulse oximetry system for high-altitude waterfowl by examining the hypoxia responses of the Andean goose (Chloephaga melanoptera). Physiol Biochem Zool. 91, 859-867.

Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR. 2018. Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol. 52, 801-811.
[Economist] [TVO] [CBC News] [Hamilton Spectator] [Global News]

Borowiec BG, O’Connor CM, Goodick K, Scott GR, Balshine S. 2018. The preference for social affiliation renders fish willing to accept lower O2 levels. Physiol Biochem Zool. 91, 716-724.

2017

Ivy CM, Scott GR. 2017. Control of breathing and ventilatory acclimatization to hypoxia in deer mice native to high altitudes. Acta Physiol. 221, 266-282.
[Editorial Feature]

Lague SL, Chua B, Alza L, Scott GR, Frappell PB, Zhong Y, Farrell AP, McCracken KG, Wang Y, Milsom WK. 2017. Divergent respiratory and cardiovascular responses to hypoxia in bar-headed geese and Andean birds. J Exp Biol. 220, 4186-4194.
[Inside JEB Feature]

Tate KB, Ivy CM, Velotta JP, Storz JF, McClelland GB, Cheviron ZA, Scott GR. 2017. Circulatory mechanisms underlying adaptive increases in thermogenic capacity in high-altitude deer mice. J Exp Biol. 220, 3616-3620.

Hawkes LA, Batbayar N, Butler PJ, Chua B, Frappell PB, Meir JU, Milsom WK, Natsagdorj T, Parr N, Scott GR, Takekawa JY, Wikelski M, Witt MJ, Bishop CM. 2017. Do bar-headed geese train for high altitude flights? Integr Comp Biol. 57, 240-251.
[Science Feature] [Outside JEB Feature]

Mahalingam S, McClelland GB, Scott GR. 2017. Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice. J Physiol. 595, 4785-4801.

Du SNN, Khajali F, Dawson NJ, Scott GR. 2017. Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution. 71, 1643-1652.

Lau DS, Connaty AD, Mahalingam S, Wall N, Cheviron ZA, Storz JF, Scott GR, McClelland GB. 2017. Acclimation to hypoxia increases carbohydrate use during exercise in high-altitude deer mice. Am J Physiol Reg Integr Comp Physiol. 312, R400-R411.

York JM, Chua BA, Ivy CM, Alza L, Cheek R, Scott GR, McCracken KG, Frappell PB, Dawson NJ, Laguë SL, Milsom WK. 2017. Respiratory mechanics of eleven avian species resident at high and low altitude. J Exp Biol. 220, 1079-1089.
[Inside JEB Feature]

McCallum ES, Du SNN, Vaseghi-Shanjani M, Choi JA, Warriner TR, Sultana T, Scott GR, Balshine S. 2017. In situ exposure to wastewater effluent reduces survival but has little effect on the behaviour or physiology of an invasive Great Lake fish. Aquat Toxicol. 184, 37-48.

Lisser DFJ, Lister ZP, Pham-Ho PQH, Scott GR, Wilkie MP. 2017. Relationship between oxidative stress and brain swelling in goldfish (Carassius auratus) exposed to high environmental ammonia. Am J Physiol Reg Integr Comp Physiol. 312, R114-R124.

Scott GR, Matey V, Mendoza JA, Gilmour KM, Perry SF, Almeida-Val VMF, Val AL. 2017. Air breathing and aquatic gas exchange during hypoxia in armoured catfish. J Comp Physiol B. 187, 117-133.

Ivy CM, Scott GR. 2017. Ventilatory acclimatization to hypoxia in mice: methodological considerations. Respir Physiol Neurobiol. 235, 95-103.

2016

Dawson NJ, Ivy CM, Alza L, Cheek R, York JM, Chua B, Milsom WK, McCracken KG, Scott GR. 2016. Mitochondrial physiology in the skeletal and cardiac muscles is altered in torrent ducks, Merganetta armata, from high altitudes in the Andes. J Exp Biol. 219, 3719-3728.

Brunt E, Turko AJ, Scott GR, Wright PA. 2016. Amphibious fish jump better on land after acclimation to a terrestrial environment. J Exp Biol. 219, 3204-3207.

Borowiec BG, Crans KD, Khajali F, Pranckevicius NA, Young A, Scott GR. 2016. Interspecific and environment-induced variation in hypoxia tolerance in sunfish. Comp Biochem Physiol A. 198, 59-71.

Du SNN, Mahalingam S, Borowiec BG, Scott GR. 2016. Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol. 219, 1130-1138.

2015

Crans KD, Pranckevicius NA, Scott GR. 2015. Physiological tradeoffs may underlie the evolution of hypoxia tolerance and exercise performance in sunfish (Centrarchidae). J Exp Biol. 218, 3264-3275.

Regan MD, RS Dhillon, DPL Toews, B Speers-Roesch, MA Sackville, S Pinto, JS Bystriansky, Scott GR. 2015. Biochemical correlates of aggressive behaviour in the Siamese fighting fish (Betta splendens). J Zool. 297, 99-107.
[Journal of Zoology 2015 Paper of the Year]

Scott GR, Elogio TS, Lui MA, Storz JF, Cheviron ZA. 2015. Adaptive modifications of muscle phenotype in high-altitude deer mice are associated with evolved changes in gene regulation. Mol Biol Evol. 32, 1962-1976.
[Editorial Feature]

Ivy CM, Scott GR. 2015. Control of breathing and the circulation in high-altitude mammals and birds. Comp Biochem Physiol A. 186, 66-74.

Lui MA, Mahalingam S, Patel P, Connaty AD, Ivy CM, Cheviron ZA, Storz JF, McClelland GB, Scott GR. 2015. High-altitude ancestry and hypoxia acclimation have distinct effects on exercise capacity and muscle phenotype in deer mice. Am J Physiol Reg Integr Comp Physiol. 308, R779-R791.

Borowiec BG, Darcy KL, Gillette DM, Scott GR. 2015. Distinct physiological strategies are used to cope with constant hypoxia and intermittent hypoxia in killifish (Fundulus heteroclitus). J Exp Biol. 218, 1198-1211.

Scott GR, Hawkes LA, Frappell PB, Butler PJ, Bishop CM, Milsom WK. 2015. How bar-headed geese fly over the Himalayas. Physiology. 30, 107-115.

Bishop CM, Spivey RJ, Hawkes LA, Batbayar N, Chua B, Frappell PB, Milsom WK, Natsagdorj T, Newman SH, Scott GR, Takekawa JY, Wikelski M, Butler PJ. 2015. The roller coaster flight strategy of bar-headed geese conserves energy during Himalayan migrations. Science. 347, 250-254.
[Outside JEB Feature] [Science News] [New Scientist] [NPR Radio] [Quirks & Quarks]

2014

Schnurr ME, Yin Y, Scott GR. 2014. Temperature during embryonic development has persistent effects on muscle energy metabolism in zebrafish. J Exp Biol. 217, 1370-1380.

Hawkes LA, Butler PJ, Frappell PB, Meir JU, Milsom WK, Scott GR, Bishop CM. 2014. Maximum running speed of captive bar-headed geese is unaffected by severe hypoxia. PLoS One. 9, e94015.
[BBC]

2013

De Boeck G, Wood CM, Iftikar FI, Matey V, Scott GR, Sloman KA, De Nazaré Paula da Silva M, Almeida-Val VMF, Val AL. 2013. Interactions between hypoxia tolerance and food deprivation in Amazonian oscars, Astronotus ocellatus. J Exp Biol. 216, 4590-4600.

Hawkes LA, Balachandran S, Batbayar N, Butler PJ, Chua B, Douglas DC, Frappell PB, Hou Y, Milsom WK, Newman SH, Prosser DJ, Sathiyaselvam P, Scott GR, Takekawa JY, Natsagdorj T, Wikelski M, Witt MJ, Yan B, Bishop CM. 2013. The paradox of extreme high-altitude migration in bar-headed geese Anser indicus. Proc R Soc B. 280, 20122114.
[Outside JEB Feature]

2012

Scott GR, Johnston IA. 2012. Temperature during embryonic development has persistent effects on thermal acclimation capacity in zebrafish. Proc Natl Acad Sci. 109, 14247-14252.
[Outside JEB Feature]

2011

Scott GR. 2011. Elevated performance: the unique physiology of birds that fly at high altitudes. J Exp Biol. 214, 2455-2462.

Scott GR, Schulte PM, Egginton S, Scott ALM, Richards JG, Milsom WK. 2011. Molecular evolution of cytochrome c oxidase underlies high-altitude adaptation in the bar-headed goose. Mol Biol Evol. 28, 351-363.
[Sightings Feature]

Hawkes LA, Scott GR, Meir JU, Frappell PB, Milsom WK. 2011. Last Word on Point:Counterpoint: High altitude is/is not for the birds! J Appl Physiol. 111, 1525.

Scott GR, Meir JU, Hawkes LA, Frappell PB, Milsom WK. 2011. Point: High altitude is for the birds! J Appl Physiol. 111, 1514-1519.

Hawkes LA, Balachandran S, Batbayar N, Butler PJ, Frappell PB, Milsom WK, Tseveenmyadag N, Newman SH, Scott GR, Sathiyaselvam P, Takekawa JT, Wikelski M, Bishop CM. 2011. The trans-Himalayan flights of bar-headed geese (Anser indicus). Proc Natl Acad Sci. 108, 9516–9519.
[Science Feature] [National Geographic Feature]

Matey V, Iftikar FI, De Boeck G, Scott GR, Sloman KA, Almeida-Val VMF, Val AL, Wood CM. 2011. Gill morphology and acute hypoxia: responses of mitochondria-rich, pavement, and mucous cells in two species with very different approaches to the osmo-respiratory compromise, the Amazonian oscar (Astronotus ocellatus) and the rainbow trout (Oncorhynchus mykiss). Can J Zool. 89, 307-324.

2010

Storz JF, Scott GR, Cheviron ZA. 2010. Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates. J Exp Biol. 213, 4125-4136.

2009

Scott GR, Richards JG, Milsom WK. 2009. Control of respiration in flight muscle from the high-altitude bar-headed goose and low-altitude birds. Am J Physiol Reg Integr Comp Physiol. 297, R1066-R1074.
[Sightings Feature]

Scott GR, Egginton S, Richards JG, Milsom WK. 2009. Evolution of muscle phenotype for extreme high altitude flight in the bar-headed goose. Proc R Soc B. 276, 3645-3653.
[Sightings Feature] [NY Times Feature] [CBC Feature]

Takekawa JY, Heath SR, Douglas DC, Perry WM, Javed S, Newman SH, Suwal RN, Rahmani AR, Choudhury BC, Prosser DJ, Yan B, Hou Y, Batbayar N, Natsagdorj T, Bishop CM, Butler PJ, Frappell PB, Milsom WK, Scott GR, Hawkes LA, Wikelski M. 2009. Geographic variation in bar-headed geese Anser indicus: connectivity of wintering areas and breeding grounds across a broad front. Wildfowl. 59, 100–123.

Sloman KA, Sloman RD, De Boeck G, Scott GR, Iftikar FI, Wood CM, Almeida-Val VMF, Val AL. 2009. The role of size in synchronous air-breathing of Hoplosternum littorale. Physiol Biochem Zool. 82, 625-634.

Wood CM, Iftikar FI, Scott GR, De Boeck G, Sloman KA, Matey V, Valdez Domingos FX, Duarte R, Almeida-Val VMF, Val AL. 2009. Regulation of gill transcellular permeability and renal function during acute hypoxia in the Amazonian oscar (Astronotus ocellatus): new angles to the osmo-respiratory compromise. J Exp Biol. 212, 1949-1964.
[Inside JEB Feature]

2008

Lee SY, Scott GR, Milsom WK. 2008. Have wing morphology or flight kinematics evolved for extreme high altitude migration in the bar-headed goose? Comp Biochem Physiol C. 148, 324-331.

Scott GR, Wood CM, Sloman KA, Iftikar FI, De Boeck G, Almeida-Val VMF,Val AL. 2008. Respiratory responses to progressive hypoxia in the Amazonian oscar, Astronotus ocellatus. Respir Physiol Neurobiol. 162, 109-116.

Scott GR, Baker DW, Schulte PM, Wood CM. 2008. Physiological and molecular mechanisms of osmoregulatory plasticity in killifish after seawater transfer. J Exp Biol. 211, 2450-2459.

Singer TD, Keir KR, Hinton M, Scott GR, McKinley RS, Schulte PM. 2008. Structure and regulation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in killifish: a comparative genomics approach. Comp Biochem Physiol D. 3, 172-185.

Scott GR, Cadena V, Tattersall GJ, Milsom WK. 2008. Body temperature depression and peripheral heat loss accompany the metabolic and ventilatory responses to hypoxia in low and high altitude birds. J Exp Biol. 211, 1326-1335.

2007

Scott GR, Milsom WK. 2007. Control of breathing and adaptation to high altitude in the bar-headed goose. Am J Physiol Reg Integr Comp Physiol. 293, R379-R391.

Wood CM, Kajimura M, Sloman KA, Scott GR, Walsh PJ, Almeida-Val VMF, Val AL. 2007. Rapid regulation of Na+ fluxes and ammonia excretion in response to acute environmental hypoxia in the Amazonian oscar, Astronotus ocellatus. Am J Physiol Reg Integr Comp Physiol. 292, R2048-R2058.

Dodd GAA, Scott GR, Milsom WK. 2007. Ventilatory roll off during sustained hypercapnia is gender specific in pekin ducks. Respir Physiol Neurobiol. 156, 47-60.

2006

Scott GR, Milsom WK. 2006. Flying high: a theoretical analysis of the factors limiting exercise performance in birds at altitude. Respir Physiol Neurobiol. 154, 284-301.

Scott GR, Schulte PM, Wood CM. 2006. Plasticity of osmoregulatory function in the killifish intestine: drinking rates, salt and water transport, and gene expression after freshwater transfer. J Exp Biol. 209, 4040-4050.

Sloman KA, Wood CM, Scott GR, S Wood, Kajimura M, Johannsson OE, Almeida-Val VMF, Val AL. 2006. Tribute to R.G. Boutilier: The effect of size on the physiological and behavioural responses of oscar, Astronotus ocellatus, to hypoxia. J Exp Biol. 209, 1197-1205.

2005

Scott GR, Keir KR, Schulte PM. 2005. Effects of spironolactone and RU486 on gene expression and cell proliferation after freshwater transfer in the euryhaline killifish. J Comp Physiol B. 175, 499-510.

Scott GR, Schulte PM. 2005. Intraspecific variation in gene expression after seawater transfer in gills of the euryhaline killifish Fundulus heteroclitus. Comp Biochem Physiol A. 141, 176-182.

Scott GR, Claiborne JB, Edwards SL, Schulte PM, Wood CM. 2005. Gene expression after freshwater transfer in gills and opercular epithelia of killifish: insight into divergent mechanisms of ion transport. J Exp Biol. 208, 2719-2729.

2004

Scott GR, Rogers JT, Richards JG, Wood CM, Schulte PM. 2004. Intraspecific divergence of ionoregulatory physiology in the euryhaline teleost Fundulus heteroclitus: possible mechanisms of freshwater adaptation. J Exp Biol. 207, 3399-3410.

Scott GR, Richards JG, Forbush B, Isenring P, Schulte PM. 2004. Changes in gene expression in gills of the euryhaline killifish Fundulus heteroclitus after abrupt salinity transfer. Am J Physiol Cell Physiol. 287, C300-C309.

Sloman KA, Scott GR, McDonald DG, Wood CM. 2004. Diminished social status affects ionoregulation at the gills and kidney in rainbow trout (Oncorhynchus mykiss). Can J Fish Aquat Sci. 61, 618-626.

Scott GR, Sloman KA. 2004. The effects of environmental pollutants on complex fish behaviour: integrating behavioural and physiological indicators of toxicity. Aquat Toxicol. 68, 369-392.

2003

Sloman KA, Scott GR, Diao Z, Rouleau C, Wood CM, McDonald DG. 2003. Cadmium affects the social behaviour of rainbow trout, Oncorhynchus mykiss. Aquat Toxicol. 65, 171-185.

Scott GR, Sloman KA, Rouleau C, Wood CM. 2003. Cadmium disrupts behavioural and physiological responses to alarm substance in juvenile rainbow trout (Oncorhynchus mykiss). J Exp Biol. 206, 1779-1790.
[Inside JEB Feature]

Book Chapters

Scott GR, Dawson NJ. 2017. Flying high: the unique physiology of birds that fly at high altitudes. In The Biology of the Avian Respiratory System: Evolution, Development, Structure and Function (ed. Maina JN), pp. 113-128. Springer.

Hawkes LA, Batbayar N, Bishop CM, Butler PJ, Frappell PB, Meir JU, Milsom WK, Natsagdorj T, Scott GR. 2017. Goose migration over the Himalayas: physiological adaptations. In Bird Migration Across the Himalayas: Wetland Functioning Amidst Mountains and Glaciers (eds. Prins HHT, Namgail T), pp. 241-253. Cambridge University Press.

McClelland GB, Scott GR. 2014. Muscle Plasticity. In The Physiology of Fishes, 4th Edition (eds. Evans DH, Claiborne JB, Currie S), pp. 1-31. CRC Press.

Scott GR, Milsom WK. 2009. Control of breathing in birds: implications for high altitude flight. In Cardio-Respiratory Control in Vertebrates: Comparative and Evolutionary Aspects (eds. Glass ML, Wood SC), pp. 429-448. Springer-Verlag.